CD1b 抗体
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北京 101111
Quick Overview for CD1b 抗体 (ABIN1981866)
抗原
See all CD1b (CD1B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD1b Purified
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特异性
- The mouse monoclonal antibody SN13 (also known as K5-1B8) recognizes an extracellular epitope of CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- A cell membrane antigen preparation that was isolated from normal human thymocytes
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亚型
- IgG1 kappa
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anti-CD1b (CD1B) (AA 18-303) antibody
CD1B 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5G3D4 unconjugated
anti-CD1b (CD1B) (AA 18-303) antibodyCD1B 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1D6B7 unconjugated
anti-CD1b (CD1B) antibody (APC)CD1B 适用: 人 FACS 宿主: 小鼠 Monoclonal SN13 APC
anti-CD1b (CD1B) (AA 1-333) antibodyCD1B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD1b (CD1B) antibodyCD1B 适用: 人 FACS, ELISA, IF, Coat 宿主: 小鼠 Monoclonal RIV12 unconjugated
anti-CD1b (CD1B) antibody (FITC)CD1B 适用: 人 FACS 宿主: 小鼠 Monoclonal SN13 FITC
anti-CD1b (CD1B) (AA 18-303) antibodyCD1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD1b (CD1B) (AA 18-303) antibodyCD1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD1b (CD1B) antibodyCD1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD1b (CD1B) antibodyCD1B 适用: 人 FACS, IF, Func 宿主: 小鼠 Monoclonal 100-1A5 unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze. Do not use after expiration date stamped on vial label.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells." in: Infection and immunity, Vol. 69, Issue 12, pp. 7461-70, (2001) (PubMed).
: "Group 1 CD1 genes in rabbit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 403-10, (2001) (PubMed).
: "Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes." in: Antimicrobial agents and chemotherapy, Vol. 42, Issue 3, pp. 550-4, (1998) (PubMed).
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: "Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells." in: Infection and immunity, Vol. 69, Issue 12, pp. 7461-70, (2001) (PubMed).
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- CD1b (CD1B)
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别名
- CD1b
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背景
- CD1b molecule,CD1b (also known as R1) together with CD1a and c, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. Besides non-peptide glycolipid antigen presentation to CD1-restricted T cells, CD1b has been implicated in thymocyte development.,R1
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基因ID
- 910
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UniProt
- P29016
抗原
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