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CCR7 抗体

CCR7 适用: 小鼠 FACS, IP 宿主: 大鼠 Monoclonal 4B12 unconjugated
产品编号 ABIN1981865
发货至: 中国
  • 抗原 See all CCR7 抗体
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CCR7 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.
    交叉反应 (详细)
    Mouse
    纯化方法
    Purified by protein-G affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Murine CD197-transfected RBL-2H3 cells
    克隆位点
    4B12
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CCR7 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Do not use after expiration date stamped on vial label.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Eisenbarth, Williams, Colegio, Meng, Strowig, Rongvaux, Henao-Mejia, Thaiss, Joly, Gonzalez, Xu, Zenewicz, Haberman, Elinav, Kleinstein, Sutterwala, Flavell: "NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." in: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).

    Huggins, Paschalidis, Flower, Perretti, DAcquisto: "Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 4, pp. 985-96, (2009) (PubMed).

  • 抗原
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    别名
    CD197 / CCR7 (CCR7 产品)
    别名
    zgc:165629 antibody, ccr7-a antibody, CD197 antibody, Cdw197 antibody, Cmkbr7 antibody, EBI1 antibody, Ebi1h antibody, BLR2 antibody, CDw197 antibody, CMKBR7 antibody, chemokine (C-C motif) receptor 7 antibody, C-C motif chemokine receptor 7 antibody, C-C motif chemokine receptor 7 L homeolog antibody, ccr7 antibody, CCR7 antibody, ccr7.L antibody, Ccr7 antibody
    背景
    Chemokine (C-C motif) receptor 7,CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.,CCR7, CC-CKR-7, EBI1
    基因ID
    12775
    UniProt
    P47774
    途径
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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