电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CCR7 抗体

Cited in 2+ publications. This 大鼠 单克隆 anti-CCR7 antibody (Clone 4B12) specifically detects CCR7 in FACS 和 IP. The antibody is reactive with 小鼠 samples.
产品编号 ABIN1981865
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCR7 抗体 (ABIN1981865)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

  • 130
  • 59
  • 46
  • 16
  • 4
  • 3
  • 2
  • 1
  • 1
小鼠

宿主

  • 86
  • 38
  • 11
  • 5
  • 3
  • 1
大鼠

克隆类型

  • 75
  • 68
  • 1
单克隆

标记

  • 60
  • 9
  • 7
  • 7
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CCR7 antibody is un-conjugated

应用范围

  • 65
  • 63
  • 33
  • 26
  • 26
  • 25
  • 19
  • 15
  • 14
  • 13
  • 8
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

4B12
  • 原理

    Anti-Ms CD197 Purified

    特异性

    The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.

    交叉反应 (详细)

    Mouse

    纯化方法

    Purified by protein-G affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Murine CD197-transfected RBL-2H3 cells

    亚型

    IgG2a kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze. Do not use after expiration date stamped on vial label.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Eisenbarth, Williams, Colegio, Meng, Strowig, Rongvaux, Henao-Mejia, Thaiss, Joly, Gonzalez, Xu, Zenewicz, Haberman, Elinav, Kleinstein, Sutterwala, Flavell: "NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." in: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).

    Huggins, Paschalidis, Flower, Perretti, DAcquisto: "Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 4, pp. 985-96, (2009) (PubMed).

  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CD197

    背景

    Chemokine (C-C motif) receptor 7,CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.,CCR7, CC-CKR-7, EBI1

    基因ID

    12775

    UniProt

    P47774

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
You are here:
Chat with us!