CCR7 抗体
Quick Overview for CCR7 抗体 (ABIN1981865)
抗原
See all CCR7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Ms CD197 Purified
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特异性
- The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.
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交叉反应 (详细)
- Mouse
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纯化方法
- Purified by protein-G affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Murine CD197-transfected RBL-2H3 cells
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亚型
- IgG2a kappa
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze. Do not use after expiration date stamped on vial label.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." in: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).
: "Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 4, pp. 985-96, (2009) (PubMed).
: "
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NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." in: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).
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- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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别名
- CD197
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背景
- Chemokine (C-C motif) receptor 7,CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.,CCR7, CC-CKR-7, EBI1
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基因ID
- 12775
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UniProt
- P47774
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途径
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
抗原
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