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CCR7 抗体

This anti-CCR7 antibody is a 大鼠 单克隆 antibody detecting CCR7 in FACS 和 IP. Suitable for 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1981865
发货至: 中国

Quick Overview for CCR7 抗体 (ABIN1981865)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CCR7 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

4B12
  • 原理

    Anti-Ms CD197 Purified

    特异性

    The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.

    交叉反应 (详细)

    Mouse

    纯化方法

    Purified by protein-G affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Murine CD197-transfected RBL-2H3 cells

    亚型

    IgG2a kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze. Do not use after expiration date stamped on vial label.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Eisenbarth, Williams, Colegio, Meng, Strowig, Rongvaux, Henao-Mejia, Thaiss, Joly, Gonzalez, Xu, Zenewicz, Haberman, Elinav, Kleinstein, Sutterwala, Flavell: "NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." in: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).

    Huggins, Paschalidis, Flower, Perretti, DAcquisto: "Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 4, pp. 985-96, (2009) (PubMed).

  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CD197

    背景

    Chemokine (C-C motif) receptor 7,CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.,CCR7, CC-CKR-7, EBI1

    基因ID

    12775

    UniProt

    P47774

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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