电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CCR7 抗体 (PE)

This anti-CCR7 antibody is a 大鼠 单克隆 antibody detecting CCR7 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1981861
发货至: 中国

Quick Overview for CCR7 抗体 (PE) (ABIN1981861)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

  • 106
  • 52
  • 36
  • 16
  • 4
  • 3
  • 2
  • 1
  • 1
小鼠

宿主

  • 79
  • 27
  • 11
  • 5
  • 1
大鼠

克隆类型

  • 72
  • 50
  • 1
单克隆

标记

  • 62
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CCR7 antibody is conjugated to PE

应用范围

  • 60
  • 60
  • 31
  • 26
  • 25
  • 16
  • 15
  • 15
  • 14
  • 13
  • 8
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

4B12
  • 原理

    Anti-Ms CD197 PE

    特异性

    The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.

    交叉反应 (详细)

    Mouse

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Murine CD197-transfected RBL-2H3 cells

    亚型

    IgG2a kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze. Avoid prolonged exposure to light.
    Do not use after expiration date stamped on vial label.
    Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Adachi, Osada, Nakamura, Tamada, Hamano: "Unique T cells with unconventional cytokine profiles induced in the livers of mice during Schistosoma mansoni infection." in: PLoS ONE, Vol. 8, Issue 12, pp. e82698, (2013) (PubMed).

    Eisenbarth, Williams, Colegio, Meng, Strowig, Rongvaux, Henao-Mejia, Thaiss, Joly, Gonzalez, Xu, Zenewicz, Haberman, Elinav, Kleinstein, Sutterwala, Flavell: "NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." in: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).

    Huggins, Paschalidis, Flower, Perretti, DAcquisto: "Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 4, pp. 985-96, (2009) (PubMed).

  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CD197

    背景

    Chemokine (C-C motif) receptor 7,CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.,CCR7, CC-CKR-7, EBI1

    基因ID

    12775

    UniProt

    P47774

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
You are here:
Chat with us!