HMGA2 抗体 (C-Term)
Quick Overview for HMGA2 抗体 (C-Term) (ABIN1981306)
抗原
See all HMGA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 64-92, C-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice." in: Chemico-biological interactions, Vol. 277, pp. 1-7, (2017) (PubMed).
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HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice." in: Chemico-biological interactions, Vol. 277, pp. 1-7, (2017) (PubMed).
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- HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))
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别名
- HMGA2
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背景
- This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 11832
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基因ID
- 8091
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NCBI登录号
- NP_003474, NP_003475
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UniProt
- P52926
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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