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HMGA2 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects HMGA2 in WB 和 FACS. It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN1981306
发货至: 中国
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Quick Overview for HMGA2 抗体 (C-Term) (ABIN1981306)

抗原

See all HMGA2 抗体
HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

适用

  • 6
  • 5

宿主

  • 6

克隆类型

  • 6
多克隆

标记

  • 6
This HMGA2 antibody is un-conjugated

应用范围

  • 6
  • 3
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB21014
  • 抗原表位

    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 64-92, C-Term

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Luo, Li, Ge, Mei, Zhao, Jiang, Geng, Li, Yao, Cao: "HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice." in: Chemico-biological interactions, Vol. 277, pp. 1-7, (2017) (PubMed).

  • 抗原

    HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

    别名

    HMGA2

    背景

    This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    分子量

    11832

    基因ID

    8091

    NCBI登录号

    NP_003474, NP_003475

    UniProt

    P52926

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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