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BCR 抗体 (Tyr177)

Name: BCR 抗体 (Tyr177)
SKU: ABIN197420
Availability: OutOfStock

BCR 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

Image no. 2 for anti-Breakpoint Cluster Region (BCR) (Tyr177) antibody (ABIN197420) (BCR 抗体 (Tyr177))

Image no. 1 for anti-Breakpoint Cluster Region (BCR) (Tyr177) antibody (ABIN197420) (BCR 抗体 (Tyr177))

2 images

产品编号 ABIN197420

发货至: 中国

Datasheet as PDF

抗原 See all BCR 抗体

BCR (Breakpoint Cluster Region (BCR))
抗原表位
30

16

8

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Tyr177
适用
95

52

25

4

2

2

1

1

1

1
人, 小鼠
宿主
88

4

4
兔
Compatible Secondaries
克隆类型
91

5
多克隆
标记
56

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This BCR antibody is un-conjugated
应用范围
67

36

33

26

26

23

17

15

9

6

5

4

3

2

1

1
Western Blotting (WB), Immunofluorescence (IF)

特异性

This antibody AP02709PU detects endogenous levels of total Bcr protein.

纯化方法

Immunoaffinity Chromatography using epitope-specific immunogen.

免疫原

The antiserum was produced against synthesized non-phosphopeptide derived from human Bcr around the phosphorylation site of tyrosine 177 (P-F-Yp-V-N).

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anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
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BCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody (in aliquots) at -20 °C.
抗原

BCR (Breakpoint Cluster Region (BCR))

别名

BCR (BCR 产品)

背景

The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.Synonyms: BCR1, Breakpoint cluster region protein, D22S11, NY-REN-26, Renal carcinoma antigen NY-REN-26

基因ID

613

NCBI登录号

NP_004318

UniProt

P11274

途径

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling