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BCR 抗体 (Tyr177)

This anti-BCR antibody is a 兔多克隆 antibody detecting BCR in WB 和 IF. Suitable for 人和小鼠.

Image no. 2 for anti-Breakpoint Cluster Region (BCR) (Tyr177) antibody (ABIN197420) (BCR 抗体 (Tyr177))

Image no. 1 for anti-Breakpoint Cluster Region (BCR) (Tyr177) antibody (ABIN197420) (BCR 抗体 (Tyr177))

2 images

产品编号 ABIN197420

发货至: 中国

Datasheet as PDF

Quick Overview for BCR 抗体 (Tyr177) (ABIN197420)

抗原

See all BCR 抗体

BCR (Breakpoint Cluster Region (BCR))

适用

98
55
26
4
2
2
1
1
1
1

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

61
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1

This BCR antibody is un-conjugated

应用范围

72
38
34
27
26
26
18
15
14
11
6
4
3
2
1
1

Western Blotting (WB), Immunofluorescence (IF)

Discover our top product BCR Primary Antibody

抗原表位
30

16

8

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Tyr177

特异性

This antibody AP02709PU detects endogenous levels of total Bcr protein.

纯化方法

Immunoaffinity Chromatography using epitope-specific immunogen.

免疫原

The antiserum was produced against synthesized non-phosphopeptide derived from human Bcr around the phosphorylation site of tyrosine 177 (P-F-Yp-V-N).
anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E5 unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibody
BCR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E11G12 unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibody
BCR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibody
BCR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (N-Term) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody (in aliquots) at -20 °C.
抗原

BCR (Breakpoint Cluster Region (BCR))

别名

BCR

背景

The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.Synonyms: BCR1, Breakpoint cluster region protein, D22S11, NY-REN-26, Renal carcinoma antigen NY-REN-26

基因ID

613

NCBI登录号

NP_004318

UniProt

P11274

途径

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling

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