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FOXO4 抗体 (Ser197)

This anti-FOXO4 antibody is a 兔 多克隆 antibody detecting FOXO4 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN197368
发货至: 中国

Quick Overview for FOXO4 抗体 (Ser197) (ABIN197368)

抗原

See all FOXO4 抗体
FOXO4 (Forkhead Box O4 (FOXO4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This FOXO4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Ser197

    特异性

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. AFX antibody AP02683PU detects endogenous levels of total AFX protein.

    纯化方法

    Immunoaffinity chromatography.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human AFX around the phosphorylation site of serine 197 (A-A-Sp-M-D).
  • 应用备注

    Suitable for use in Western blot (1: 500-1: 1000) and Immunohistochemistry (1: 50-1: 100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    FOXO4 (Forkhead Box O4 (FOXO4))

    别名

    FOXO4 / AFX1 / MLLT7

    背景

    FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4

    基因ID

    4303

    NCBI登录号

    NP_001164402

    UniProt

    P98177

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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