FOXO4 抗体 (Ser197)
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Quick Overview for FOXO4 抗体 (Ser197) (ABIN197368)
抗原
See all FOXO4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser197
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特异性
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. AFX antibody AP02683PU detects endogenous levels of total AFX protein.
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纯化方法
- Immunoaffinity chromatography.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human AFX around the phosphorylation site of serine 197 (A-A-Sp-M-D).
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应用备注
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Suitable for use in Western blot (1: 500-1: 1000) and Immunohistochemistry (1: 50-1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- FOXO4 (Forkhead Box O4 (FOXO4))
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别名
- FOXO4 / AFX1 / MLLT7
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背景
- FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4
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基因ID
- 4303
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NCBI登录号
- NP_001164402
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UniProt
- P98177
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
抗原
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