PKC mu 抗体 (Ser738)
Quick Overview for PKC mu 抗体 (Ser738) (ABIN197312)
抗原
See all PKC mu (PRKD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser738
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特异性
- This antibody detects endogenous levels of total PKD/PKCμ protein.
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纯化方法
- Immunoaffinity Chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human PKD/PKCmy around the phosphorylation site of serine 738 (E-K-Sp-F-R).
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anti-Protein Kinase D1 (PRKD1) antibody
PRKD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (pTyr463) antibodyPRKD1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (pSer910) antibodyPRKD1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 314-404) antibodyPRKD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 1-912) antibodyPRKD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 233-246) antibodyVerified PRKD1 适用: 人 WB, ELISA, IHC, IP 宿主: 山羊 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 383-395) antibodyVerified PRKD1 适用: 人 WB, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 361-389), (N-Term) antibodyPRKD1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1037 unconjugated
anti-Protein Kinase D1 (PRKD1) (AA 171-220) antibodyPRKD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase D1 (PRKD1) (pSer205) antibodyPRKD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
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别名
- PRKD1
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背景
- Protein Kinase C mu, is a ~140 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival, metastasis and transcriptional regulation. PKC mu (also known as Protein Kinase D or PKD) is implicated in the regulation of multiple cellular processes including Golgi organization and membrane transport in epithelial cells. PKC mu is phosphorylated on serine 742 (serine 748 for the mouse sequence) in the activation loop in a PKC-dependent pathway, mainly by PKC eta and PKC epsilon. This is critical for its catalytic activity, substrate phosphorylation and role in activating the ERK1 MAP Kinase signaling cascade.Synonyms: PKC D1, PKC mu, PKD, PKD1, PRKCM, Protein kinase C mu type, Protein kinase D, Serine/threonine-protein kinase D1, nPKC-D1, nPKC-mu
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基因ID
- 5587
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NCBI登录号
- NP_002733
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UniProt
- Q15139
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途径
- Myometrial Relaxation and Contraction
抗原
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