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Ezrin 抗体 (Tyr353)

The 兔 多克隆 anti-Ezrin antibody is suitable to detect Ezrin in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN197258
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Ezrin 抗体 (Tyr353) (ABIN197258)

抗原

See all Ezrin (EZR) 抗体
Ezrin (EZR)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Ezrin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Tyr353

    特异性

    Ezrin antibody detects endogenous levels of total Ezrin protein.

    纯化方法

    Affinity-chromatography using epitope-specific immunogen

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 353 (Q-D-YP-E-E).
  • 应用备注

    Western Blot: 1: 500approx. 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    Ezrin (EZR)

    别名

    Ezrin

    背景

    Ezrin (also known as p81, 80K, or cytovillin) is a cytoplasmic protein which is enriched in microvilli and other cell surface structures. Its NH2-terminal domain is associated with the plasma membrane and the COOH-terminal domain with the cytoskeleton. Ezrin has an actin-binding capability. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas. Ezrin serves as a tyrosine kinase substrate, and is phosphorylated in EGF-stimulated cells.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81

    基因ID

    7430

    NCBI登录号

    NP_001104547

    UniProt

    P15311

    途径

    Maintenance of Protein Location
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