JunD 抗体 (Ser255)
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北京 101111
Quick Overview for JunD 抗体 (Ser255) (ABIN197142)
抗原
See all JunD (JUND) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser255
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特异性
- JunD antibody detects endogenous levels of total JunD protein.
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纯化方法
- Affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthetic non-phosphopeptide derived from human JunD around the phosphorylation site of serine 255 (G-E-Sp-P-P).
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anti-Jun D Proto-Oncogene (JUND) (pSer255) antibody
JUND 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) antibodyKD Validated JUND 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6560 unconjugated Recombinant Antibody
anti-Jun D Proto-Oncogene (JUND) antibodyJUND 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) (N-Term) antibodyJUND 适用: 人 WB, IP, ChIP-seq, CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) (pSer255) antibodyJUND 适用: 人 WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) antibodyJUND 适用: 人 WB, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) (Ser255) antibodyJUND 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) (pSer255) antibodyJUND 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) antibodyJUND 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Jun D Proto-Oncogene (JUND) (pSer100), (pSer73) antibodyJUND 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50approx. 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS( without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- JunD (JUND) (Jun D Proto-Oncogene (JUND))
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别名
- Jun-D
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背景
- JunD is the most broadly expressed member of the Jun family and the AP1 transcription factor complex. It has been found that primary fibroblasts lacking murine JunD displayed p53-dependent growth arrest, upregulated p19(ARF) expression, and premature senescence. In contrast, immortalized cell lines lacking JunD showed increased proliferation and higher cyclin D1 levels. These properties were reminiscent of the effects of oncogenic RAS expression on primary and established cell cultures. Furthermore, JunD -/- fibroblasts exhibited increased p53-dependent apoptosis upon ultraviolet irradiation and were sensitive to the cytotoxic effects of tumor necrosis factor-alpha. The antiapoptotic role of JunD was confirmed using an in vivo model of TNF-mediated hepatitis. The authors proposed that JunD protects cells from senescence, or apoptotic responses to stress stimuli, by acting as a modulator of the signaling pathways that link RAS to p53.Synonyms: JUND, Transcription factor jun-D
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基因ID
- 3727
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NCBI登录号
- NP_005345
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UniProt
- P17535
抗原
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