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BCR 抗体 (pTyr177)

The 兔多克隆 anti-BCR antibody (ABIN196938) specifically detects BCR in WB 和 IHC (p). The antibody is reactive with 人和小鼠 samples.

Image no. 1 for anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody (ABIN196938) (BCR 抗体 (pTyr177))

2 images

产品编号 ABIN196938

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

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Quick Overview for BCR 抗体 (pTyr177) (ABIN196938)

抗原

See all BCR 抗体

BCR (Breakpoint Cluster Region (BCR))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This BCR antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

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pTyr177

特异性

This antibody detects endogenous levels of Bcr only when phosphorylated at Tyrosine 177.

纯化方法

Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

The antiserum was produced against synthesized phosphopeptide derived from Human Bcr around the phosphorylation site of Tyrosine 177 (P-F-Yp-V-N).
anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E5 unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibody
BCR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E11G12 unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) antibody
KD Validated BCR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB6945 unconjugated Recombinant Antibody

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibody
BCR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-100) antibody
BCR 适用: 人, 小鼠, 大鼠 WB, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibody
BCR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (N-Term) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 50-100) antibody
BCR 适用: 人 ICC, IF/ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Suitable for use in Western blot (1/500-1/1000) and Immunohistochemistry onParaffin-Embedded Sections (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody (in aliquots) at -20 °C.
抗原

BCR (Breakpoint Cluster Region (BCR))

别名

BCR

背景

The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.Synonyms: BCR1, Breakpoint cluster region protein, D22S11, NY-REN-26, Renal carcinoma antigen NY-REN-26

基因ID

613

NCBI登录号

NP_004318

UniProt

P11274

途径

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling