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FOXO4 抗体 (pSer197)

FOXO4 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN196850
发货至: 中国
  • 抗原 See all FOXO4 抗体
    FOXO4 (Forkhead Box O4 (FOXO4))
    抗原表位
    • 20
    • 18
    • 16
    • 10
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer197
    适用
    • 140
    • 72
    • 64
    • 10
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 138
    • 1
    • 1
    克隆类型
    • 127
    • 13
    多克隆
    标记
    • 68
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This FOXO4 antibody is un-conjugated
    应用范围
    • 108
    • 50
    • 39
    • 39
    • 25
    • 18
    • 17
    • 9
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. AFX (phospho-Ser197) antibody detects endogenous levels of AFX only when phosphorylated at serine 197.
    纯化方法
    Immunoaffinity chromatography.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from human AFX around the phosphorylation site of serine 197 (A-A-SP-M-D).
    Top Product
    Discover our top product FOXO4 Primary Antibody
  • 应用备注
    Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    FOXO4 (Forkhead Box O4 (FOXO4))
    别名
    FOXO4 / AFX1 / MLLT7 (FOXO4 产品)
    别名
    FOXO4 antibody, foxo4 antibody, AFX antibody, AFX1 antibody, MLLT7 antibody, Afxh antibody, Mllt7 antibody, afx antibody, RGD1561201 antibody, forkhead box O4 antibody, forkhead box O4 L homeolog antibody, FOXO4 antibody, foxo4.L antibody, Foxo4 antibody
    背景
    FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4
    基因ID
    4303
    NCBI登录号
    NP_001164402
    UniProt
    P98177
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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