CDC25C 抗体 (pSer216)
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Quick Overview for CDC25C 抗体 (pSer216) (ABIN196818)
抗原
See all CDC25C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer216
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特异性
- This antibody detects endogenous levels of CDC25C only when phosphorylated at Serine 216.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic phosphopeptide derived from human cdc25C around the phosphorylation site of Serine 216 (S-P-Sp-M-P).
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应用备注
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Suitable for use in Immunohistochemistry (1/50approx. 1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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别名
- CDC25C
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背景
- Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.Synonyms: Cell Division Cycle 25C, Dual specificity phosphatase Cdc25C, M-phase inducer phosphatase 3
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基因ID
- 995
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NCBI登录号
- NP_001781
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UniProt
- P30307
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途径
- Cell Division Cycle, M Phase
抗原
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