电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

FOXO1 抗体 (pSer256)

The 兔 多克隆 anti-FOXO1 antibody (ABIN196812) specifically detects FOXO1 in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN196812
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FOXO1 抗体 (pSer256) (ABIN196812)

抗原

See all FOXO1 抗体
FOXO1 (Forkhead Box O1 (FOXO1))

适用

  • 267
  • 200
  • 176
  • 51
  • 33
  • 25
  • 18
  • 13
  • 9
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 244
  • 25
  • 1

克隆类型

  • 211
  • 59
多克隆

标记

  • 126
  • 12
  • 9
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
This FOXO1 antibody is un-conjugated

应用范围

  • 223
  • 91
  • 90
  • 78
  • 75
  • 61
  • 59
  • 41
  • 40
  • 19
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 29
    • 23
    • 22
    • 21
    • 18
    • 16
    • 16
    • 16
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer256

    特异性

    This antibody detects endogenous levels of FKHR only when phosphorylated at Serine 256.

    纯化方法

    Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    The antiserum was produced against synthesized phosphopeptide derived from human FKHR around the phosphorylation site of serine 256 (A-A-SP-M-D).
  • 应用备注

    Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    FOXO1 (Forkhead Box O1 (FOXO1))

    别名

    FOXO1A

    背景

    FOXO1A (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Chromosomal aberrations involving FOXO1A are a cause of rhabdomyosarcoma 2 (RMS2), also known as alveolar rhabdomyosarcoma.Synonyms: FKHR, FOXO1, Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead in Rhabdomyosarcoma

    基因ID

    2308

    NCBI登录号

    NP_002006

    UniProt

    Q12778

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
You are here: