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CXCR3 抗体

CXCR3 适用: 人 FACS, IHC, Neut, Func 宿主: 小鼠 Monoclonal 2AR1 unconjugated
产品编号 ABIN1967162
发货至: 中国
  • 抗原 See all CXCR3 抗体
    CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
    适用
    • 75
    • 39
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    宿主
    • 71
    • 12
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    小鼠
    克隆类型
    • 63
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    单克隆
    标记
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    This CXCR3 antibody is un-conjugated
    应用范围
    • 59
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut), Functional Studies (Func)
    特异性
    Recognizes human CXCR3. Reacts specifically with CXCR3 transfectants and not the parental cell line using FACS analysis. Does not cross-react with CXCR1, CXCR2, CXCR4 or transfectants.
    纯化方法
    Protein G purified
    免疫原
    CXCR3 transfected NS0 cells.

    Type of Immunogen: Cells
    克隆位点
    2AR1
    亚型
    IgG1
    Top Product
    Discover our top product CXCR3 Primary Antibody
  • 应用备注
    Approved: Flo (5 - 10 μg/mL), Func, IHC (10 μg/mL), Neut

    Usage: Suitable for use in Neutralization, Flow Cytometry and Immunohistochemistry. Neutralization (ND50): The exact concentration required to neutralize human cell surface CXCR3 activity is dependent on the ligand concentration as well as the number of CXCR3 receptors present on the cell surface. The Neutralization Dose50 (ND50) is defined as the concentration of antibody required to yield one half maximal inhibition of the cell surface CXCR3 mediated rhl-TAC response on a responsive cell line, at a specific rhl-TAC concentration. The ND50 for this lot was determined to be ~1-6 μg/mL in the presence of 7 ng/mL of rhl-TAC, using the hCXCR3 transfected BaF/3 cells in a chemotaxis assay. Flow Cytometry: 5-10 μg/mL, Add 10 μL to 1-2.5x10^5 cells in total reaction volume 200 μL. Visualize binding by adding 10 μL of 25 μg/mL IgG (FITC) goat anti-mouse. Immunohistochemistry: 10 μg/mL detected CXCR3 in human tonsil. Cells were fixed in PBS, 4 % paraformaldehyde and blocked with PBS, 10 % normal donkey serum, 0.1 % Triton X-100, 1 % BSA. Cells were washed with PBS, BSA.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    200 μL sterile PBS
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS, 5 % trehalose.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
  • 抗原
    CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
    别名
    CXCR3 (CXCR3 产品)
    别名
    CD182 antibody, CD183 antibody, CKR-L2 antibody, CMKAR3 antibody, GPR9 antibody, IP10-R antibody, Mig-R antibody, MigR antibody, Cd183 antibody, Cmkar3 antibody, CXCR3 antibody, cxcr3 antibody, Gpr9 antibody, CXC-R3 antibody, CXCR-3 antibody, zgc:92301 antibody, sb:eu378 antibody, C-X-C motif chemokine receptor 3 antibody, chemokine (C-X-C motif) receptor 3 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 antibody, CXCR3 antibody, Cxcr3 antibody, cxcr3 antibody, cxcr3.2 antibody, cxcr3.1 antibody
    背景
    Name/Gene ID: CXCR3
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CXCR3, C-x-c chemokine receptor 3, CD183 antigen, CKR-L2, CXCR-3, CMKAR3, CD182, CD183, Cxcr3a, GPR9, IP-10 receptor, IP10-R, Mig receptor, MigR, Mig-R, Chemokine (C-X-C) receptor 3, CXC-R3, Cxcr3b, G protein-coupled receptor 9, IP10 receptor
    基因ID
    2833
    UniProt
    P49682
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