GATA1 抗体 (pSer142)
Quick Overview for GATA1 抗体 (pSer142) (ABIN196684)
抗原
See all GATA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer142
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特异性
- GATA-1 (phospho-Ser142) antibody detects endogenous levels of GATA-1 only when phosphorylated at serine 142.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Synthetic phosphopeptide derived from human GATA-1 around the phosphorylation site of serine 142 (R-L-SP-P-D).
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anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (pSer142) antibody
GATA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (Internal Region) antibodyVerified GATA1 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 123-199) antibodyGATA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) antibodyGATA1 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4F5 unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 39-153) antibodyGATA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 1-413) antibodyGATA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 20-265) antibodyGATA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (pSer310) antibodyGATA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (pSer310) antibodyGATA1 适用: 人, 小鼠, 大鼠, 猴, 犬, Cow, 兔, 马 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) antibodyGATA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G1 unconjugated
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应用备注
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Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl containing 0.02 % Sodium Azide as preservative and 50 % glycerol as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
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别名
- GATA1
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背景
- GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch from fetal hemoglobin production to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.Synonyms: ERYF1, Eryf1, Erythroid transcription factor, GATA-1, GATA-binding factor 1, GF-1, GF1, NF-E1 DNA-binding protein
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基因ID
- 2623
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NCBI登录号
- NP_002040
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UniProt
- P15976
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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