HSP90AA1 抗体 (AA 229-263)
Quick Overview for HSP90AA1 抗体 (AA 229-263) (ABIN1945096)
抗原
See all HSP90AA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 229-263
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This hsp90a.1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 229-263 amino acids from the Central region of human (DANRE) hsp90a.1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:2000. WB: 1:2000. WB: 1:1000. WB: 1:2000. IHC-P: 1:25
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
: "The zebrafish reference genome sequence and its relationship to the human genome." in: Nature, Vol. 496, Issue 7446, pp. 498-503, (2013) (PubMed).
: "Shuttling of the chaperones Unc45b and Hsp90a between the A band and the Z line of the myofibril." in: The Journal of cell biology, Vol. 180, Issue 6, pp. 1163-75, (2008) (PubMed).
: "The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis." in: Developmental biology, Vol. 308, Issue 1, pp. 133-43, (2007) (PubMed).
: "Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90." in: Developmental biology, Vol. 210, Issue 1, pp. 56-70, (1999) (PubMed).
: "HSP 90 alpha and HSP 90 beta genes are present in the zebrafish and are differentially regulated in developing embryos." in: Biochemical and biophysical research communications, Vol. 204, Issue 2, pp. 746-52, (1994) (PubMed).
-
: "The zebrafish reference genome sequence and its relationship to the human genome." in: Nature, Vol. 496, Issue 7446, pp. 498-503, (2013) (PubMed).
-
- HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))
-
别名
- hsp90a.1
-
背景
- Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.
-
分子量
- 83319
-
基因ID
- 30591
-
UniProt
- Q90474
-
途径
- M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
-