ERI1 抗体
(2 references)Quick Overview for ERI1 抗体 (ABIN1944959)
抗原
See all ERI1 抗体适用
宿主
克隆类型
标记
应用范围
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亚型
- IgG
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anti-Exoribonuclease 1 (ERI1) antibody
ERI1 适用: 人, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 2-66) antibodyERI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 1-345) antibodyERI1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (N-Term) antibodyERI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 51-150) antibodyERI1 适用: 小鼠 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 231-280) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 29-78) antibodyERI1 适用: 人, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 2-249) antibodyERI1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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储存条件
- 4 °C,-20 °C
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: "Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30447-54, (2006) (PubMed).
: "A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans." in: Nature, Vol. 427, Issue 6975, pp. 645-9, (2004) (PubMed).
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: "Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30447-54, (2006) (PubMed).
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- ERI1 (Exoribonuclease 1 (ERI1))
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别名
- ERI1
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背景
- RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication- dependent histone pre-mRNAs.
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分子量
- 40064 Da
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基因ID
- 90459
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UniProt
- Q8IV48
抗原
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