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Calreticulin 抗体

This anti-Calreticulin antibody is a 兔 多克隆 antibody detecting Calreticulin in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1944947
发货至: 中国

Quick Overview for Calreticulin 抗体 (ABIN1944947)

抗原

See all Calreticulin (CALR) 抗体
Calreticulin (CALR)

适用

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  • 9
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  • 5
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  • 1
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人, 小鼠, 大鼠

宿主

  • 137
  • 25
  • 2
  • 1

克隆类型

  • 126
  • 39
多克隆

标记

  • 97
  • 13
  • 12
  • 7
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Calreticulin antibody is un-conjugated

应用范围

  • 134
  • 87
  • 57
  • 49
  • 47
  • 43
  • 34
  • 15
  • 14
  • 13
  • 3
  • 2
  • 2
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  • 1
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  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 亚型

    IgG
  • 应用备注

    IF: 1:100. WB: 1:1000. IHC: 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    储存条件

    4 °C,-20 °C
  • Goshima, Kawamura, Fukumoto, Miura, Honma, Satoh, Wakamatsu, Yamamoto, Kimura, Nishikawa, Andoh, Iida, Ishikawa, Ito, Kagawa, Kaminaga, Kanehori, Kawakami, Kenmochi, Kimura, Kobayashi, Kuroita et al.: "Human protein factory for converting the transcriptome into an in vitro-expressed proteome,. ..." in: Nature methods, Vol. 5, Issue 12, pp. 1011-7, (2008) (PubMed).

    McCauliffe, Yang, Wilson, Sontheimer, Capra: "The 5'-flanking region of the human calreticulin gene shares homology with the human GRP78, GRP94, and protein disulfide isomerase promoters." in: The Journal of biological chemistry, Vol. 267, Issue 4, pp. 2557-62, (1992) (PubMed).

    Rokeach, Haselby, Meilof, Smeenk, Unnasch, Greene, Hoch: "Characterization of the autoantigen calreticulin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 9, pp. 3031-9, (1991) (PubMed).

    McCauliffe, Lux, Lieu, Sanz, Hanke, Newkirk, Bachinski, Itoh, Siciliano, Reichlin: "Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen." in: The Journal of clinical investigation, Vol. 85, Issue 5, pp. 1379-91, (1990) (PubMed).

  • 抗原

    Calreticulin (CALR)

    别名

    CALR

    背景

    Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).

    分子量

    48142 Da

    基因ID

    811

    UniProt

    P27797

    途径

    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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