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PPARA 抗体 (AA 1-468)

Name: PPARA 抗体 (AA 1-468)
SKU: ABIN1944858
Availability: OutOfStock

This anti-PPARA antibody is a 小鼠单克隆 antibody detecting PPARA in WB, FACS, IF 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of lysates from Hela, Jurkat, mouse NIH/3T3 cell line (from left to right), using ARA Antibody (ABIN1944858 and ABIN2838532). (PPARA 抗体 (AA 1-468))

Immunohistochemical analysis of paraffin-embedded H. (PPARA 抗体 (AA 1-468))

IHC (p)

Fluorescent image of Hela cells stained with ARA Antibody (ABIN1944858 and ABIN2838532). (PPARA 抗体 (AA 1-468))

IHC (p)

Flow cytometric analysis of Hela cells using ARA Antibody (green, Cat(ABIN1944858 and ABIN2838532)) compared to an isotype control of mouse IgG1(blue). (PPARA 抗体 (AA 1-468))

FACS

5 images

(4 references)

产品编号 ABIN1944858

发货至: 中国

Quick Overview for PPARA 抗体 (AA 1-468) (ABIN1944858)

抗原

See all PPARA 抗体

PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

适用

人, 小鼠

宿主

小鼠

克隆类型

单克隆

标记

This PPARA antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1331CT894-186-143

Discover our top product PPARA Primary Antibody

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AA 1-468

纯化方法

This antibody is purified through a protein G column, followed by dialysis against PBS.

免疫原

This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.

亚型

IgG1 kappa
anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 301-400) antibody
PPARA 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 61-170) antibody
PPARA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-120) antibody
PPARA 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5D10C3 unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibody
KO Validated PPARA 适用: 人 WB, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (AA 1-120) antibody
PPARA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5D10E10 unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (C-Term) antibody
PPARA 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 山羊, 豚鼠, 兔, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibody
PPARA 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF, FM 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (pSer12) antibody
PPARA 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibody
PPARA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) (N-Term) antibody
PPARA 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 山羊, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:25. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Cho, Lee, Choi, Yang, Tae Hong, Kim, Yoon: "Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha." in: Immunopharmacology and immunotoxicology, Vol. 31, Issue 3, pp. 459-67, (2009) (PubMed).

Kobayashi, Kodani, Nozawa, Endo, Sawasaki: "DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system." in: FEBS letters, Vol. 582, Issue 18, pp. 2737-44, (2008) (PubMed).

Tugwood, Aldridge, Lambe, Macdonald, Woodyatt: "Peroxisome proliferator-activated receptors: structures and function." in: Annals of the New York Academy of Sciences, Vol. 804, pp. 252-65, (1997) (PubMed).

Mukherjee, Jow, Noonan, McDonnell: "Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators." in: The Journal of steroid biochemistry and molecular biology, Vol. 51, Issue 3-4, pp. 157-66, (1995) (PubMed).
抗原

PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

别名

PPARA

背景

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

分子量

52225

基因ID

5465

UniProt

Q07869

途径

Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C