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BCL10 抗体 (AA 1-143)

This anti-BCL10 antibody is a 小鼠 单克隆 antibody detecting BCL10 in WB, FACS 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1944800
发货至: 中国

Quick Overview for BCL10 抗体 (AA 1-143) (ABIN1944800)

抗原

See all BCL10 抗体
BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

适用

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宿主

  • 95
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小鼠

克隆类型

  • 68
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单克隆

标记

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This BCL10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1185CT13-2-1-2
  • 抗原表位

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    AA 1-143

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10.

    亚型

    IgG1 kappa
  • 应用备注

    WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Koseki, Inohara, Chen, Carrio, Merino, Hottiger, Nabel, Núñez: "CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 9955-61, (1999) (PubMed).

    Thome, Martinon, Hofmann, Rubio, Steiner, Schneider, Mattmann, Tschopp: "Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 9962-8, (1999) (PubMed).

    Yan, Lee, Schilbach, Goddard, Dixit: "mE10, a novel caspase recruitment domain-containing proapoptotic molecule." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10287-92, (1999) (PubMed).

  • 抗原

    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

    别名

    BCL10

    背景

    Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

    分子量

    26252

    基因ID

    8915

    UniProt

    O95999

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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