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USP11 抗体 (N-Term)

This anti-USP11 antibody is a 小鼠 单克隆 antibody detecting USP11 in WB 和 FACS. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1944797
发货至: 中国

Quick Overview for USP11 抗体 (N-Term) (ABIN1944797)

抗原

See all USP11 抗体
USP11 (Ubiquitin Specific Peptidase 11 (USP11))

适用

  • 45
  • 12
  • 12
  • 1
  • 1

宿主

  • 38
  • 6
  • 1
小鼠

克隆类型

  • 31
  • 14
单克隆

标记

  • 26
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This USP11 antibody is un-conjugated

应用范围

  • 31
  • 17
  • 12
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

1220CT620-193-189
  • 抗原表位

    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 32-300, N-Term

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11.

    亚型

    IgG1 kappa
  • 应用备注

    WB: 1:1000. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Yamaguchi, Kimura, Miki, Yoshida: "The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha)." in: The Journal of biological chemistry, Vol. 282, Issue 47, pp. 33943-8, (2007) (PubMed).

    Schoenfeld, Apgar, Dolios, Wang, Aaronson: "BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage." in: Molecular and cellular biology, Vol. 24, Issue 17, pp. 7444-55, (2004) (PubMed).

    Ideguchi, Ueda, Tanaka, Yang, Tsuji, Ohno, Hagiwara, Aoki, Ishigatsubo: "Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM." in: The Biochemical journal, Vol. 367, Issue Pt 1, pp. 87-95, (2002) (PubMed).

    Swanson, Freund, Ploder, McInnes, Valle: "A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders." in: Human molecular genetics, Vol. 5, Issue 4, pp. 533-8, (1996) (PubMed).

  • 抗原

    USP11 (Ubiquitin Specific Peptidase 11 (USP11))

    别名

    USP11

    背景

    Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.

    分子量

    109817

    基因ID

    8237

    UniProt

    P51784
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