MAGED1 抗体 (AA 20-224)
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北京 101111
Quick Overview for MAGED1 抗体 (AA 20-224) (ABIN1944790)
抗原
See all MAGED1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-224
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.
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亚型
- IgG1 kappa
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anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 635-834) antibody
MAGED1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 117-226) antibodyMAGED1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyMAGED1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyKD Validated MAGED1 适用: 人 WB, IF (p) 宿主: 小鼠 Monoclonal 25GB8200 unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 1-778) antibodyMAGED1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 579-778) antibodyMAGED1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 117-226) antibodyMAGED1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyMAGED1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 1-778) antibodyMAGED1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyMAGED1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation." in: FEBS letters, Vol. 564, Issue 1-2, pp. 171-6, (2004) (PubMed).
: "NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis." in: Neuron, Vol. 27, Issue 2, pp. 279-88, (2000) (PubMed).
: "Identification of a new, unorthodox member of the MAGE gene family." in: Genomics, Vol. 59, Issue 2, pp. 161-7, (1999) (PubMed).
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: "hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation." in: FEBS letters, Vol. 564, Issue 1-2, pp. 171-6, (2004) (PubMed).
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- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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别名
- MAGED1
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背景
- Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
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分子量
- 86161
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基因ID
- 9500
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UniProt
- Q9Y5V3
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途径
- Neurotrophin Signaling Pathway
抗原
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