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CD300a 抗体 (PE)

This PE-conjugated 小鼠 单克隆 anti-CD300a antibody (Clone MEM-260) specifically detects CD300a in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN192409
发货至: 中国
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Quick Overview for CD300a 抗体 (PE) (ABIN192409)

抗原

See all CD300a (CD300A) 抗体
CD300a (CD300A)

适用

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宿主

  • 17
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小鼠

克隆类型

  • 20
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单克隆

标记

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This CD300a antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-260
  • 原理

    Anti-Hu CD300a PE

    特异性

    The antibody MEM-260 reacts with an extracellular epitope of CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25 % of circulating T cells and 15 % of circulating B cells.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    HPB human acute lymphoid leukemia cell line

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 溶解方式

    No reconstitution is necessary.

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    CD300a (CD300A)

    别名

    CD300a

    背景

    CD300a molecule,CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.,IRC, CLM-8, IGSF12, CMRF35H

    基因ID

    11314

    UniProt

    Q9UGN4

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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