ADIPOQ 抗体
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北京 101111
Quick Overview for ADIPOQ 抗体 (ABIN192012)
抗原
See all ADIPOQ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects Adiponectin.
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产品特性
- Synonyms: ADIPOQ, ACDC, ACRP30, APM1, GBP28, Adipocyte, C1q and collagen domain-containingprotein, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30kDa protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein
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纯化方法
- Protein G chromatography
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免疫原
- Recombinant human Adiponectin from E. coli
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in aqua bidest to 1 mg/mL.
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缓冲液
- PBS pH 7,4
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储存条件
- 4 °C/-20 °C
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储存方法
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Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- Adiponectin
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背景
- Adipose cells produce and secrete numerous physiologically important proteins, such as Lipoprotein Lipase, Leptin, and Adipocyte Complement Related protein of 30 kDa, also known as Acrp30 or Adiponectin. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, Adiponectin mRNA is induced >100 fold. Adiponectin improves the ability of insulin to suppress glucose production, at sub physiological levels, thereby linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol 3 kinase (PI3K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. Adiponectin mRNA is significantly reduced in adipose tissue of obese patients with Type 2 diabetes. The structural similarity of Adiponectin to TNF alpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Adiponectin is implicated as a regulator of whole body energy homeostasis.Synonyms: 30 kDa adipocyte complement-related protein, ACDC, ACRP30, ADIPOQ, APM1, Adipocyte, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, C1q and collagen domain-containing protein, GBP28, Gelatin-binding protein
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基因ID
- 9370
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UniProt
- Q15848
抗原
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