MSTN 抗体
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北京 101111
Quick Overview for MSTN 抗体 (ABIN191941)
抗原
See all MSTN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects Myostatin prodomain.
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产品特性
- Synonyms: MSTN, GDF8, GDF-8, Growth differentiation factor 8
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纯化方法
- Protein G Chromatography
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免疫原
- Recombinant Myostatin
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亚型
- IgG2b
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in aqua bidest to 1 mg/mL.
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缓冲液
- 50 mM TRIS, pH 7.4
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储存条件
- 4 °C/-20 °C
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储存方法
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Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- MSTN (Myostatin (MSTN))
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别名
- Myostatin
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背景
- Myostatin (GDF8) is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor ß superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70 % ) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.Synonyms: GDF-8, GDF8, Growth differentiation factor 8, MSTN
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基因ID
- 2660
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UniProt
- O14793
抗原
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