NPPB 抗体 (N-Term)
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Quick Overview for NPPB 抗体 (N-Term) (ABIN191931)
抗原
See all NPPB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-32, N-Term
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特异性
- This antibody detects synthetic BNP (aa 1-32) and recombinant proBNP (aa 1-108).
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纯化方法
- Protein G chromatography
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免疫原
- Synthetic human BNP (aa 1-32) KLH conjugatedAA Sequence: SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
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亚型
- IgG2b
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in aqua bidest to 1 mg/mL.
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缓冲液
- PBS pH 7,4
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储存条件
- 4 °C/-20 °C
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储存方法
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Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- NPPB (Natriuretic Peptides B (NPPB))
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别名
- Natriuretic Peptides B
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背景
- In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
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基因ID
- 4879
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UniProt
- P16860
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途径
- Hormone Activity
抗原
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