IBSP 抗体
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Quick Overview for IBSP 抗体 (ABIN191813)
抗原
See all IBSP 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Bone Sialoprotein. There were no cross reactivities obtained with Human Osteonectin, Human Osteopontin and Human Alkaline Phosphatase.
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纯化方法
- Purified
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免疫原
- Human Bone Sialoprotein (bone extract)
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应用备注
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ELISA (1 μg/mL). RIA (20 ng/mL). Flow Cytometry. Western blot (2 ng/mL). Immunohistochemistry on Paraffin Sections (2 ng/mL). Immunocytochemistry (1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in aqua bidest to initial volume.
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缓冲液
- PBS, pH 7.4 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C and reconstituted at -20 °C.
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- IBSP (Integrin-Binding Sialoprotein (IBSP))
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别名
- Bone Sialoprotein 2
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背景
- The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately 12 % of the noncollagenous proteins in human bone. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.Synonyms: BNSP, BSP II, Bone sialoprotein II, Cell-binding sialoprotein, IBSP, Integrin-binding sialoprotein
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基因ID
- 3381
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NCBI登录号
- NP_004958
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UniProt
- P21815
抗原
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