At least three isoforms of SPATA18 are known to exist, this antibody will detect the two longest isoforms. SPATA18 antibody is predicted to not cross-react with other SPATA family members.
纯化方法
Affinity chromatography purified via peptide column
免疫原
19 amino acid peptide near the amino terminus of human SPATA18.
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
SPATA18, also known as SPETEX-1, was initially identified as a cytoplasmic protein of elongate spermatids that is thought to be involved in differentiation process of elongate spermatids to mature spermatozoa.Recent experiments have shown that SPATA18 is a transcriptional target of p53 and p63.It has also been suggested to play a role in mitochondria quality control by inducing intramitochondrial lysosome-like organella that eliminate oxidized mitochondrial proteins. Synonyms: Spermatogenesis associated protein 18, MIEAP, SPETEX1