IRGC 抗体 (N-Term)
Quick Overview for IRGC 抗体 (N-Term) (ABIN1887842)
抗原
See all IRGC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Two isoforms of IRGC are known to exist, this antibody will only recognize the IRGCa isoform.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 13 amino acid peptide near the amino terminus of human IRGC.
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anti-Immunity-Related GTPase Family, Cinema (IRGC) (C-Term) antibody
IRGC 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Immunity-Related GTPase Family, Cinema (IRGC) (AA 73-122) antibodyIRGC 适用: 人, 大鼠, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Immunity-Related GTPase Family, Cinema (IRGC) (C-Term) antibodyIRGC 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
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别名
- IRGC
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背景
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Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens.IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans.Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs.In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines.As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
Synonyms: Immunity-related GTPase cinema 1, Interferon-inducible GTPase 5, Iigp5, CINEMA -
NCBI登录号
- NP_062558
抗原
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