BANP 抗体 (Center)
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北京 101111
Quick Overview for BANP 抗体 (Center) (ABIN1887517)
抗原
See all BANP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 14 amino acid peptide near the center of human BANP.
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anti-Protein BANP (BANP) (AA 1-260) antibody
BANP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein BANP (BANP) (AA 1-469) antibodyBANP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein BANP (BANP) (AA 30-390) antibodyBANP 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1524CT337-6-32 unconjugated
anti-Protein BANP (BANP) antibodyBANP 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- BANP (Protein BANP (BANP))
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别名
- BANP
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背景
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BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen.BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest.p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop.BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling.Furthermore, BANP can modulate NF-kappaB transactivation and can inhibit tumorigenesis by regulating NF-kappaB target genes.Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.
Synonyms: BTG3 associated nuclear protein, BEND1, SMAR1, SMARBP1 -
NCBI登录号
- NP_001167014
抗原
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