Influenza A Virus Neuraminidase 抗体 (C-Term)
Quick Overview for Influenza A Virus Neuraminidase 抗体 (C-Term) (ABIN1887449)
抗原
See all Influenza A Virus Neuraminidase (NA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Synthetic peptide corresponding to 15 amino acids at the carboxy terminus of the avian influenza neuraminidase protein.Efforts were made to use relatively conserved regions as the antigen.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- Influenza A Virus Neuraminidase (NA)
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别名
- Influenza A Virus Neuraminidase
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物质类
- Influenza Protein
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背景
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Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA.Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics.Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found.These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes.During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong.There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low.Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus.
Synonyms: Neuraminidase
抗原
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