FEM1B
适用: 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 594
限制
仅限研究用
状态
Liquid
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
F1A-ALPHA antibody, F1AA antibody, FEM1-beta antibody, FEM1B antibody, mKIAA0396 antibody, fem-1 homolog B antibody, protein fem-1 homolog B antibody, fem-1 homolog B L homeolog antibody, fem-1 homolog b (C. elegans) antibody, feminization 1 homolog b (C. elegans) antibody, FEM1B antibody, Fem1b antibody, LOC413692 antibody, fem1b.L antibody, fem1b antibody
背景
Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family.A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1beta.F1Aalpha/FEM1beta is the homologue of C.elegans sex determining protein FEM-1.FEM-1/F1Aalpha is cleaved by CED-3 and caspase.FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1.Overexpression of F1Aalpha induces apoptosis.F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis.F1Aalpha is expressed in a variety of human and mouse tissues. Synonyms: F1A alpha