IL22R 抗体 (AA 560-574)
This anti-IL22R antibody is a 兔 多克隆 antibody detecting IL22R in WB 和 ELISA. Suitable for 人 和 大鼠.
Quick Overview for IL22R 抗体 (AA 560-574) (ABIN1886889)
抗原
IL22R
(Interleukin 22 Receptor (IL22R))
适用
人, 大鼠
宿主
兔
克隆类型
多克隆
标记
This IL22R antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- AA 560-574
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Synthetic peptide corresponding to amino acids 560 to 574 of human IL-22 receptor precursor.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- IL22R (Interleukin 22 Receptor (IL22R))
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背景
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A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified.The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family.IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling.IL-22 and its receptor activate JAK-STAT signaling pathway.IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10.A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently.IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity.LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
Synonyms: IL22R -
分子量
- 62 kDa
抗原
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