TRAF3IP2 抗体 (AA 554-568)
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北京 101111
Quick Overview for TRAF3IP2 抗体 (AA 554-568) (ABIN1886888)
抗原
See all TRAF3IP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 554-568
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Synthetic peptide corresponding to amino acids 554 to 568 of human CIKS.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))
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别名
- CIKS
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背景
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Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses.NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli.NF-kappaB associates with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity.IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma.A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kappaB activator 1).CIKS directly interacts with IKKgamma.CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK).These results indicate that CIKS/Act1 is involved in the inflammation and stress responses.CIKS/Act1 is ubiquitously expressed in human tissues.
Synonyms: Act1 -
分子量
- 63 kDa
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途径
- Production of Molecular Mediator of Immune Response
抗原
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