CARD9 抗体 (AA 521-536)
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Quick Overview for CARD9 抗体 (AA 521-536) (ABIN1886886)
抗原
See all CARD9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 521-536
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Synthetic peptide corresponding to amino acids 521 to 536 of human CARD9.The sequence is different from that of rat origin by two amino acids.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))
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别名
- CARD9
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背景
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Apoptosis is related to many diseases and development.Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules.CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC.A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10.CARD9 associates with BCL-10 and forms a complex within cells.CARD9 induces apoptosis and activates NF-kappaB.CARD9 is an upstream activator of BCL-10 and NF-kappaB signaling.
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分子量
- 59 kDa
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途径
- Activation of Innate immune Response
抗原
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