MPRIP 抗体 (AA 473-486)
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北京 101111
Quick Overview for MPRIP 抗体 (AA 473-486) (ABIN1886882)
抗原
See all MPRIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 473-486
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Peptide corresponding to amino acids 473 to 486 of murine RIP3.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
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别名
- RIP3
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背景
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Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis.Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family.A novel member in the RIP kinase family was recently identified and designated RIP3.RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain.RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kappaB activation.Overexpression of RIP3 induces apoptosis and NF-kappaB activation.The messenger RNA of RIP3 is expressed in a subset of adult tissues.
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分子量
- 57 kDa
抗原
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