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DRAK2 抗体 (AA 351-365)

This anti-DRAK2 antibody is a 兔 多克隆 antibody detecting DRAK2 in ELISA, WB 和 ICC. Suitable for 人.
产品编号 ABIN1886873
发货至: 中国

Quick Overview for DRAK2 抗体 (AA 351-365) (ABIN1886873)

抗原

See all DRAK2 (STK17B) 抗体
DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

适用

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宿主

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克隆类型

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多克隆

标记

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This DRAK2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 351-365

    交叉反应 (详细)

    It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.

    纯化方法

    Ion exchange chromatography purified

    免疫原

    Peptide corresponding to amino acids 351 to 365 of human DRAK2.
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid freezing and thawing repeatly.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原

    DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

    别名

    DRAK2

    背景

    Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases).DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain.Overexpression of DRAK2 induces apoptosis.DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities.DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
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