DNASE2
适用: 人, 小鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
限制
仅限研究用
状态
Liquid
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
抗原
DNASE2
(Deoxyribonuclease II, Lysosomal (DNASE2))
别名
DNase II
背景
Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation.These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus.DNase II causes both chromatin condensation and DNA fragmentation.The genes encoding human, porcine, and murine DNase II have been cloned.The DNase II gene encodes a 40 kDa proenzyme.The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing.Overexpression of DNase II induces chromatin condensation.DNase II is ubiquitously expressed in human tissues. Synonyms: DNase II