MTBP 抗体 (AA 122-139)
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北京 101111
Quick Overview for MTBP 抗体 (AA 122-139) (ABIN1886842)
抗原
See all MTBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 122-139
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Synthetic peptide corresponding to amino acids 122 to 139 of human MTBP, which differ from the mouse sequence by three amino acids.
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anti-MDM2 Binding Protein (MTBP) (AA 853-881), (C-Term) antibody
MTBP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20020 unconjugated
anti-MDM2 Binding Protein (MTBP) antibodyMTBP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibodyMTBP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 23-350) antibodyMTBP 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 122-139) antibodyMTBP 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 122-139), (Middle Region) antibodyMTBP 适用: 人 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- MTBP (MDM2 Binding Protein (MTBP))
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别名
- MTBP
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背景
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The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2 and MTBP, were recently discovered.The transcriptional activity of p53 is modulated by posttranslational regulations of the p53 protein including stabilization and acetylation.P53 transcriptionally activates MDM2 gene then the translated MDM2 protein binds to p53 and promotes the degradation of p53 leading to lowering the concentration of p53 protein.MDM2 inhibits both p53 mediated G1 arrest and apoptosis.A recently discovered protein termed MTBP was found to bind to MDM2 and to inhibit the modulation effect of MDM2 on p53.MTBP is expressed in a variety of normal tissues.
Synonyms: MTBP -
分子量
- 104 kDa
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NCBI登录号
- NP_071328
抗原
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