IPO7 抗体 (AA 976-1038)
Our Local Distributor
北京 101111
Quick Overview for IPO7 抗体 (AA 976-1038) (ABIN1886728)
抗原
See all IPO7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 976-1038
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 976 and 1038 of Importin-7
-
-
-
-
应用备注
-
Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 1 x PBS, 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- IPO7 (Importin 7 (IPO7))
-
别名
- Importin-7
-
背景
-
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal.The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta.Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin.This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.[provided by RefSeq]
-
分子量
- 120 kDa
-
基因ID
- 10527
-
NCBI登录号
- NM_006391, NP_006382
-
途径
- Protein targeting to Nucleus
抗原
-