CKMT1B 抗体 (AA 63-297)
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北京 101111
Quick Overview for CKMT1B 抗体 (AA 63-297) (ABIN1886588)
抗原
See all CKMT1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-297
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 63 and 297 of Human CKMT1B
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
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别名
- Creatine kinase(mitochondrial 1B)
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背景
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Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine.It belongs to the creatine kinase isoenzyme family.It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes.Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes.Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis.Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.[provided by RefSeq]
Synonyms: CKMT, CKMT1, UMTCK -
分子量
- 47 kDa
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基因ID
- 1159
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NCBI登录号
- NP_066270, NM_020990
抗原
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