beta Amyloid 抗体 (AA 602-757)
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Quick Overview for beta Amyloid 抗体 (AA 602-757) (ABIN1886574)
抗原
See all beta Amyloid (Abeta) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 602-757
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 602 and 757 of Human APP
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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别名
- beta-Amyloid
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背景
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This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides.Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).Multiple transcript variants encoding several different isoforms have been found for this gene.[provided by RefSeq]
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分子量
- 87 kDa
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基因ID
- 351
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NCBI登录号
- NM_000484, NP_000475
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途径
- Inflammasome
抗原
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