IL12RB1 抗体 (AA 57-458)
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北京 101111
Quick Overview for IL12RB1 抗体 (AA 57-458) (ABIN1886561)
抗原
See all IL12RB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 57-458
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 57 and 458 of Human IL12RB1
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anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 420-470) antibody
IL12RB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibodyIL12RB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 37-234) antibodyIL12RB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 197-348) antibodyIL12RB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 25-305) antibodyIL12RB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 119-280) antibodyIL12RB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (Internal Region) antibodyVerified IL12RB1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibodyIL12RB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
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背景
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The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily.This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex.This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity.The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections.Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]
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分子量
- 73 kDa
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基因ID
- 3594
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NCBI登录号
- NM_005535, NP_005526
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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