Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
限制
仅限研究用
状态
Liquid
缓冲液
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
储存液
Thimerosal (Merthiolate)
注意事项
Biohazard Informations: This product contains thimerosal which is hazardous.
储存条件
4 °C/-20 °C
储存方法
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原
RASSF1
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
别名
RASSF1
背景
This gene encodes a protein similar to the RAS effector proteins.Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene.The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region.The encoded protein was found to interact with DNA repair protein XPA.The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest.Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]