FGD4 抗体 (AA 49-297)
This anti-FGD4 antibody is a 兔 多克隆 antibody detecting FGD4 in WB, IF 和 IHC. Suitable for 人.
Quick Overview for FGD4 抗体 (AA 49-297) (ABIN1886512)
抗原
See all FGD4 抗体
FGD4
(FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
适用
人
宿主
兔
克隆类型
多克隆
标记
This FGD4 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
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抗原表位
- AA 49-297
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 49 and 297 of FGD4
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anti-FYVE, RhoGEF and PH Domain Containing 4 (FGD4) antibody
FGD4 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 4 (FGD4) (AA 99-198) antibodyFGD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
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别名
- FGD4
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背景
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This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape.This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes.This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP.The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract.Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system.[provided by RefSeq]
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分子量
- 87 kDa
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基因ID
- 121512
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NCBI登录号
- NM_139241, NP_640334
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途径
- Neurotrophin Signaling Pathway
抗原
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