SAFB 抗体 (AA 476-705)
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北京 101111
Quick Overview for SAFB 抗体 (AA 476-705) (ABIN1886502)
抗原
See all SAFB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 476-705
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 476 and 705 of HET/ SAF B
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- SAFB (Scaffold Attachment Factor B (SAFB))
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别名
- HET/ SAF B
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背景
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This gene encodes a DNA-binding protein that has highfor scaffold or matrix attachment region DNA elements (S/MAR DNA).This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein.Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR.This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes.It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor.This gene is a candidate gene for breast tumorigenesis.[provided by RefSeq]
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分子量
- 103 kDa
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基因ID
- 6294
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NCBI登录号
- NM_002967, NP_002958
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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