UNC13(C. Elegans)-Like (AA 462-719) 抗体
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北京 101111
Quick Overview for UNC13(C. Elegans)-Like (AA 462-719) 抗体 (ABIN1886489)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 462-719
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 462 and 719 of human UNC13B
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- UNC13(C. Elegans)-Like
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背景
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This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia.The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain.Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia.Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.[provided by RefSeq]
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分子量
- 181 kDa
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基因ID
- 10497
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NCBI登录号
- NP_006368, NM_006377
抗原
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