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B-Cell Linker 抗体 (AA 394-456)

Name: B-Cell Linker 抗体 (AA 394-456)
SKU: ABIN1886429
Availability: OutOfStock

BLNK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN1886429

发货至: 中国

Datasheet as PDF

抗原 See all B-Cell Linker (BLNK) 抗体

B-Cell Linker (BLNK)
抗原表位
22

18

17

15

9

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 394-456
适用
95

68

38

3

3

2

2

2

1

1

1
人
宿主
105

8

1
兔
Compatible Secondaries
克隆类型
106

8
多克隆
标记
48

7

6

6

4

4

4

4

4

4

4

4

4

4

4

2

1
This B-Cell Linker antibody is un-conjugated
应用范围
107

52

36

26

20

19

18

7

6

6

2

1

1
Western Blotting (WB), Immunofluorescence (IF)

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Synthetic peptide contain a sequence corresponding to a region within amino acids 394 and 456 of BLNK

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anti-B-Cell Linker (BLNK) (N-Term) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) (pTyr96) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

限制

仅限研究用
状态

Liquid

缓冲液

1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

储存液

Thimerosal (Merthiolate)

注意事项

Biohazard Informations: This product contains thimerosal which is hazardous.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原

B-Cell Linker (BLNK)

别名

B-cell linker protein (BLNK 产品)

别名

BLNK antibody, blnk antibody, MGC147045 antibody, BASH antibody, Bca antibody, Ly-57 antibody, Ly57 antibody, Lyw-57 antibody, SLP-65 antibody, AGM4 antibody, BLNK-S antibody, LY57 antibody, SLP65 antibody, bca antibody, B-cell linker antibody, B cell linker antibody, BLNK antibody, blnk antibody, Blnk antibody

背景

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development.This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions.The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation.Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked.Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

分子量

50 kDa

基因ID

29760

NCBI登录号

NP_037446, NM_013314

途径

BCR Signaling