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B-Cell Linker 抗体 (AA 394-456)

This anti-B-Cell Linker antibody is a 兔 多克隆 antibody detecting B-Cell Linker in WB 和 IF. Suitable for 人.
产品编号 ABIN1886429
发货至: 中国

Quick Overview for B-Cell Linker 抗体 (AA 394-456) (ABIN1886429)

抗原

See all B-Cell Linker (BLNK) 抗体
B-Cell Linker (BLNK)

适用

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宿主

  • 117
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克隆类型

  • 116
  • 10
多克隆

标记

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This B-Cell Linker antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 394-456

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Synthetic peptide contain a sequence corresponding to a region within amino acids 394 and 456 of BLNK
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    B-Cell Linker (BLNK)

    别名

    B-cell linker protein

    背景

    This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development.This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions.The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation.Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked.Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

    分子量

    50 kDa

    基因ID

    29760

    NCBI登录号

    NP_037446, NM_013314

    途径

    BCR Signaling
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